Head of the Clinical Research Division
Hematologist of the Department of Hemoblastosis Chemotherapy and Bone Marrow and Hematopoietic Stem Cell Transplantation
Candidate of Medical Sciences
In 2009, Mikhail Y. Drokov graduated with honors from the Pirogov Russian National Research Medical University with a degree in general medicine. That same year he began working in the Department of Bone Marrow Transplantation as a hematologist. In 2010, in parallel with his work activity, he received a diploma in applied informatics. Mikhail Drokov’s diploma work was the development of an accounting system for the Laboratory of Cryopreservation of Stem Cells and Bone Marrow of the Hematological Research Center now called the National Medical Research Center for Hematology.
In 2011, he completed an internship at the Transplant & Cellular Therapy Center (Prof. P. McCarthy) and carried out scientific work at the Department of Cell Stress Biology (Prof. A. Gudkov) at the Roswell Park Comprehensive Cancer Center in Buffalo, NY.
In 2014, under the guidance of Academician of the Russian Academy of Sciences V.G. Savchenko, Mikhail Y. Drokov defended his degree for Candidate of Medical Sciences with the thesis, “Investigation of the Expression of Granzyme B in CD4 + Lymphocytes and T-regulatory Cells in Patients after Allogeneic Bone Marrow Transplantation.”
Mikhail Drokov’s scientific work is primarily focused on bone marrow transplantation and the introduction of modern regimens for the prevention of graft-versus-host reactions (mainly with the use of post-transplant cyclophosphamide), into working practice.
Another important area of focus is the diagnosis of graft-versus-host disease with intestinal lesions (including its steroid-refractory form) and its therapy.
Additionally, the study of the T-cell link of the immune system in patients after transplantation holds an important place in the scientific work of Mikhail Drokov.
In parallel with clinical practice, a lot of work has been carried out and is currently continuing in the field of transplant immunology, which is carried out in the Laboratory for Immunophenotyping of Blood and Bone Marrow Cells (head of the laboratory – Cand. Sci. (Med.), Irina V. Galtseva).
Another area of focus is work on the informatization and systematization of transplantation data. Already within the framework of the Department of Chemotherapy of Hemoblastosis, Hematopoiesis Depressions and BMT, a configuration was developed on the 1C: Enterprise 8.3 platform to record and systematize data on transplantation beginning in 1988. Currently, this system covers many divisions of the NMRC for Hematology and allows for the systemization of scientific information about patients before and after transplantation.
In 2019, a website for post-transplant patients ( tkm.blood.ru ) was launched , which posted video recommendations (“Patient Schools”) recorded by the staff of the day hospital for post-transplant patients (head of the department – Cand. Sci. (Med.), V.A. Vasilieva).
Another key project developed by Mikhail Drokov was the web portal, “Self-Observation Portal of Patients after BMT,” which allows for the aggregation and systemization of information on the current state of patient health after transplantation, both in the hospital and outside, which has improved control over this extremely difficult category of patients.
Since 2021, Mikhail Drokov has been a consultant on the development of transplantation in the Republic of Uzbekistan. The center in Tashkent has successfully implemented the previously developed methods. In 2022, he received the gratitude of the Minister of the Republic of Uzbekistan.
He has been a member of the APBMT (Asia-Pacific Bone Marrow Transplantation Organization) since 2023. In the same year, he became a member of the Central Standardization Committee in the same organization. In 2024, he became a member of the ASTCT (American Society for Transplantation and Cellular Therapy).
M.Y. Drokov is the author of more than 370 publications, including publications in foreign journals. He has edited 2 books on allogeneic hematopoietic stem cell transplantation.
