Patents

Title: "Method of identification of Candida spp. and other yeast-like fungi from positive hemoculture by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in patients with bloodstream infection".

Description of the Invention: The invention relates to the field of medicine, in particular to microbiology. A method for identifying yeast-like fungi of the genus Candida and the genus Rhodotorula, including sample preparation of positive hemoculture and identification of yeast-like fungi by matrix-assisted activated laser desorption ionization time-of-flight mass spectrometry.

Scope of application: (IPC class): G01N 33/48, G01N 33/00, G01N 2800/00 (20.08)

Authors: Galina Aleksandrovna Klyasova, Anna Olegovna Malchikova, Hunan Levonovich Julhakyan.

Title: "Method of obtaining cryopreserved mononuclear cells"

Description of the Invention: The invention relates to the field of medicine, namely transfusiology and transplantology. It can be used for the prevention and treatment of both acute and chronic graft versus host reactions, rejection during transplantation of allogeneic organs and therapy of cutaneous T-cell lymphomas, as well as a number of autoimmune diseases.

Scope of application: (IPC class): A61N 1/02 (2006.01)

Authors: Vera Alekseevna Vasilieva, Denis Vladimirovich Kamelskikh, Nikolai Mikhailovich Kapranov, Ksenia Aleksandrovna Nikiforova, Yulia Olegovna Davydova, Natalia Arnoldovna Petinati, Nina Iosifovna Drize, Larisa Anatolyevna Kuzmina, Irina Vladimirovna Galtseva, Tatiana Vladimirovna Gaponova

Title: "Induction method of antigen-associated immune response"

Description of the Invention: The invention relates to the field of medicine and can be used for the prevention and treatment of the graft-versus-host reaction, rejection during transplantation of allogeneic organs, cutaneous T-cell lymphomas, as well as a number of autoimmune diseases.

Scope of application: (IPC class): A61K 35/17 (2015.01) A61P37/00 (2006.01) A01N 1/02 (2006.01)

Authors: Vera Alekseevna Vasilieva, Denis Vladimirovich Kamelskikh, Nikolai Mikhailovich Kapranov, Ksenia Aleksandrovna Nikiforova, Yulia Olegovna Davydova, Natalia Arnoldovna Petinati, Nina Iosifovna Drize, Larisa Anatolyevna Kuzmina, Irina Vladimirovna Galtseva, Tatiana Vladimirovna Gaponova

Title: "Method of identification of bacteria from positive hemocultures by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in patients with bloodstream infection"

Description of the Invention: The invention relates to the field of medicine, in particular to microbiology, with the possibility of application in patients in hematology, and can be used to identify bacteria from positive hemoculture by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in patients with bloodstream infection.

Scope of application: (IPC class): C12Q1/04 (2006.01) G01N 23/00 (2006.01) G01N 33/49 (2006.01) C12N1/20 (2006.01) C12R 1/01 (2006.01)

Authors: Galina Aleksandrovna Klyasova, Anna Olegovna Malchikova, Hunan Levonovich Julhakyan

Title: "Method of identification of Candida spp. and other yeast-like fungi from positive hemoculture by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in patients with bloodstream infection"

Description of the Invention: The invention relates to the field of medicine, in particular to microbiology with the possibility of application for patients in hematology, and can be used to identify Candida spp. and other yeast-like fungi from positive hemoculture using the method of matrix laser desorption ionization time-of-flight mass spectrometry, in particular in patients with bloodstream infection.

Scope of application: (IPC class): C12Q1/04 (2006.01) G01N 23/00 (2006.01) G01N 33/49 (2006.01) C12N1/16 (2006.01) C12R 1/72 (2006.01)

Authors: Galina Aleksandrovna Klyasova, Anna Olegovna Malchikova, Hunan Levonovich Julhakyan

Title: "A test system for conducting studies of the hemostatic properties of local wound coatings in vitro"

Description of the Invention: The invention relates to the pharmaceutical industry, namely to test systems for laboratory studies of the hemostatic properties of local wound coatings in vitro.

Scope of application: (IPC class): G01N 33/48 (2006.01) G01N 1/28 (2006.01) A61J 1/00 (2006.01) A61L 15/16 (2006.01)

Authors: Galina Gennadievna Belozerskaya, Valery Alekseevich Kabak, Evgeny Mikhailovich Golubev, Tatiana Ivanovna Shirokova, Andrey Pavlovich Momot, Dmitry Evgenievich Belozerov, Marina Vladimirovna Pihteeva, Olga Evgenievna Nevedrova, Hunan Levonovich Julhakyan, Larisa Sergeevna Malikhina, Dmitry Yurievich Bychichko, Assaf Rudolfovich Lempert, Maxim Sergeevich Mironov, Yulia Sergeevna Logvinova

Title: "Method for determining the severity of pathological infiltration of the bone marrow in Gaucher disease"

Description of the Invention: The invention relates to the field of medicine, in particular to hematology, and can be used to diagnose pathological involvement of the bone marrow in patients with Gaucher disease (GD).

Scope of application: (IPC class): A61B 5/055 (2006.01) G16H 30/40 (2006.01)

Authors: Anastasia Alexandrovna Solovieva, Galina Alexandrovna Yatsyk, Vasily Evgenievich Mamonov, Kira Anatolyevna Lukina, Radion Viktorovich Ponomarev, Elena Pavlovna Sysoeva, Rolanda Borisovna Chavynchak, Sergey Mikhailovich Kulikov, Hunan Levonovich Julhakyan, Elena Alekseevna Lukina

Title: "A method for predicting the renal response to antimyeloma therapy in patients with myeloma cast nephropathy, acute renal injury and the need for dialysis"

Description of the Invention: The invention relates to the field of medicine, in particular to hematology, and can be used to predict the renal response to antimyeloma therapy in myeloma cast nephropathy with acute renal injury with the need for dialysis.

Scope of application: (IPC class): G01N 33/52 (2006.01) G01N 33/53 (2006.01)

Authors: Irina Germanovna Rekhtina, Larisa Pavlovna Mendeleeva, Evgenia Valeryevna Kazarina, Valentina Nikolaevna Dvirnyk, Ekaterina Sergeevna Stolyarevich, Alla Mikhailovna Kovrigina, Sergey Mikhailovich Kulikov

Title: "A method for assessing minimal residual disease (MRD) by multicolored flow cytofluorimetry in patients with acute myeloid leukemia (AML) in the post-induction phase of treatment"

Description of the Invention: The invention relates to medicine, namely to hematology, and can be used to determine the prognosis of relapse in patients with acute myeloid leukemia (AML) based on the results of the evaluation of the minimal residual disease (MRD) in the post-induction phase of treatment after the 1st control point - in the period from the 35th to the 42nd day after the 1st course of induction chemotherapy and the 2nd control point - in the period from the 70th to the 84th day after the 2nd course of induction chemotherapy.

Scope of application: (IPC/CPC class): G01N 21/64, C12Q1/68 (2006.01) / G01N 21/64, C12Q1/68 (2021.08.)

Authors: Irina Vladimirovna Galtseva, Irina Anatolyevna Lukyanova, Yulia Olegovna Davydova, Nikolai Mikhailovich Kapranov, Ksenia Aleksandrovna Nikiforova, Sergey Mikhailovich Kulikov, Elena Nikolaevna Parovichnikova

Title: "Container for the division into doses, storage and clinical use of blood components, cell suspensions and liquids (variants)"

Description of the invention: This group of inventions relates to the field of biotechnology, pharmacy, medicine, in particular, to transfusiology.

Scope of application: (IPC/CPC class): A61J 1/05 (2006.01)

Authors: Denis Vladimirovich Kamelskikh, Valeria Konstantinovna Luchkina, Maria Evgenievna Kolomiichenko

Title: "Method for determining the risk group for patients with multiple myeloma complicated by plasmacytoma"

Description of the Invention: The invention relates to medicine, namely to hematology, and can be used to determine the risk group for patients with multiple myeloma (MM) complicated by plasmacytoma.

Scope of application: (IPC/CPC class): G01N 33/574, G01N 33/50, C12Q 1/25

Authors: Maya Valeryevna Solovieva, Maxim Valeryevich Soloviev, Alla Mikhailovna Kovrigina, Tatiana Nikiforovna Obukhova, Larisa Pavlovna Mendeleeva

Title: "Method for determining the absolute length of leukocyte telomeres using the method of flow cytometry"

Description of the Invention: The invention relates to medicine and clinical and laboratory practice, namely, to a method for determining the absolute length of leukocyte telomeres by flow cytometry based on regression analysis with the results of determining the length of telomeres using a polymerase chain reaction in real time.

Scope of application: (IPC/CPC class): G01N 21/64, C12Q1/68 (2006.01) / G01N 21/64, C12Q1/68 (2021.08.

Authors: Irina Vladimirovna Galtseva, Yulia Olegovna Davydova, Nikolai Mikhailovich Kapranov, Anton Vladimirovich Luchkin, Larisa Pavlovna Mendeleeva, Valeriy Grigoryevich Savchenko, Maxim Leonidovich Filipenko

Title: "Test system and method for detecting deletions of the long arm of chromosome 6"

Description of the Invention: The invention relates to a set of oligonucleotide primers for the specific amplification of twenty microsatellite loci of the long arm of the human chromosome 6 (6q), which can be used in a test system to determine deletions of the long arm of chromosome 6 (6q) by multiplex polymerase chain reaction (PCR), as well as in a method for identifying patients at risk of an unfavorable course of follicular lymphoma by the presence of significant deletions of the long arm of chromosome 6 (6q) using the aforementioned test system.

Scope of application: (IPC class): C12Q1/6844, C12Q 2531/113, G01N 33/5017, (2021.08)

Authors: Ksenia Andreevna Sychevskaya, Sergey Kirillovich Kravchenko, Andrey Borisovich Sudarikov

Title: "Test system and method for detecting SESN1 gene deletions"

Description of the Invention: The invention relates to the field of medicine, oncology, in particular hematology. A pool of oligonucleotide primers has been proposed for the specific amplification of six microsatellite loci of SESN1 gene introns, which can be used in a test system for determining SESN1 gene deletions by multiplex polymerase chain reaction (PCR), as well as in a method for detecting patients with an unfavorable course of follicular lymphoma by the presence of significant SESN1 gene deletions using the aforementioned test system.

Scope of application: (IPC class): C12Q 2531/113, G01N 33/50, (2006.01)

Authors: Ksenia Andreevna Sychevskaya, Sergey Kirillovich Kravchenko, Andrey Borisovich Sudarikov

Title: "Four-chamber container for dose division, storage and clinical use of blood components (other liquids)"

Scope of application: (LOC class): 24-02

Authors: Denis Vladimirovich Kamelskikh, Vitaly Sergeevich Davydov, Yulia Olegovna Davydova

Title: "Four-chamber container for sampling blood components, dividing them into samples, storage and use"

Scope of application: (LOC class): 24-02

Authors: Denis Vladimirovich Kamelskikh, Vitaly Sergeevich Davydov, Yulia Olegovna Davydova